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Flynn LT, Gao WJ
Mol Psychiatry. 2023 Sep 7. doi: 10.1038/s41380-023-02235-4. Online ahead of print. PMID: 37679470

Linda A. Chamberlin1, 2, Sha-Sha Yang1, 3, Erin P. McEachern1, Joshua T. M. Lucas4, Owen W. McLeod II5, Claire A. Rolland5, Nancy R. Mack1, Brielle R. Ferguson1, 6, Wen-Jun Gao1
Neuropsychopharmacology. 2023 Apr 11. PMID: 37041206 DOI: 10.1038/s41386-023-01576-6 (2023)

Nadia N. Bouras, Nancy R. Mack*, and Wen-Jun Gao*
Frontiers in Systems Neuroscience (2023)

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Mack NR, Deng S, Yang SS, Shu Y, Gao WJ
Neuroscientist. 2022 Jan 27:10738584211069071. doi: 10.1177/10738584211069071. Online ahead of print. PMID: 35086369

(Drexel Library Access)
Bo Xing, Nancy R. Mack, Yu-xiang Zhang, Erin P. McEachern, Wen-Jun Gao
J Neurosci. 42(2):313-324. doi: 10.1523/JNEUROSCI.0741-21.2021. Epub 2021 Nov 29. PMID: 34844989 (January 12, 2022)

(Drexel Library Access)
Yu-xiang Zhang, Bo Xing, Yan-chun Li, Chun-xia Yan, Wen-Jun Gao
Neuropharmacology. 204:108895. doi: 10.1016/j.neuropharm.2021.108895. Epub 2021 Nov 20. PMID: 34813859 (February 15, 2022)

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(Drexel Library Access)
Shasha Yang, Nancy R. Mack, Yousheng Shu, Wen-Jun Gao
Front Neural Circuits. 15:716408. doi: 10.3389/fncir.2021.716408. eCollection 2021. PMID: 34322002 (July 12, 2021)

(Drexel Library Access)
Wen-Jun Gao, Shasha Yang, Nancy R. Mack, Linda A. Chamberlin
Mol Psychiatry. 10.1038/s41380-021-01196-w. doi: 10.1038/s41380-021-01196-w. Online ahead of print. PMID: 34163013 (June 23, 2021)

"Prepubertal environment enrichment prevents psychosis-related dopamine dysregulation in a neurodevelopmental model for schizophrenia"
Nancy R. Mack and Wen-Jun Gao
Biological Psychiatry, 89(3):212-214. (2021, commentary)

"From hyposociability to hypersociability -the effects of PSD-95 deficiency on the dysfunctional development of social behavior"
Wen-Jun Gao* and Nancy R. Mack
Frontiers in Behavioral Neuroscience, 28 January 2021 | https://doi.org/10.3389/fnbeh.2021.618397. (2021, perspective)

• *Commentary: April Pruitt and AZA Stephen Allsop (2021): Understanding the Role of a Molecularly Defined Social Circuit. Biological Psychiatry, 89(5):421-423

"A subpopulation of prefrontal cortical neurons is required for social memory"
Bo Xing1, Nancy R. Mack1, Kai-Ming Guo2,3, Yu-Xiang Zhang1, Billy Ramirez1, Sha-Sha Yang1, Li Lin2*, Dong V. Wang1, Yan-Chun Li1, and Wen-Jun Gao1*
Biological Psychiatry (accepted). Biological Psychiatry, 89(5):521-531. September 04, 2020DOI:https://doi.org/10.1016/j.biopsych.2020.08.023 (2021)

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"PSD-95 deficiency alters GABAergic inhibition in the prefrontal cortex"
Erin P. McEachern, Austin A. Coley, Sha-Sha Yang, Wen-Jun Gao
Neuropharmacology, available online 18 August 2020, 108277. (2020)

"The Paraventricular Nucleus of the Thalamus is an Important Node in the Emotional Processing Network"
Jessica R. Barson, Nancy R. Mack, Wen-Jun Gao
Frontiers in Behavioral Neuroscience, section Emotion Regulation and Processing. 14:191 (2020, invited review)

Yan-Chun Li, Priyalakshmi Panikker, Bo Xing, Sha-Sha Yang, Cassandra Alexandropoulos, Erin P McEachern, Rita Akumuo, Elise Zhao, Yelena Gulchina, Mikhail V. Pletnikov, Nikhil M. Urs, Marc G. Caron, Felice Elefant, and Wen-Jun Gao
Biological Psychiatry. 87:745-755. pii: S0006-3223(19)31828-1. doi: 10.1016/j.biopsych.2019.10.025. [Epub ahead of print] PMID: 31892408 (2020)

• Commentary:
  Michael F. Jackson
  Biological Psychiatry, 87:692-694

Monaco SA, Matamoros AJ, Gao WJ
Prog Neuropsychopharmacol Biol Psychiatry;100:109901. doi: 10.1016/j.pnpbp.2020.109901 (Epub Feb 27, 2020) Jun 8, 2020

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Austin Coley and Wen-Jun Gao
Scientific Reports, 9:9486 (July 1, 2019)

"Sonic hedgehog signaling in astrocytes mediates cell-type specific synaptic organization"
Steven Hill, Andrew Blaeser, Austin A. Coley, Katherine A. Shepard, Corey Harwell, Wen-Jun Gao, A. Denise R. Garcia
eLife; [Epub ahead of print] 8. pii: e45545. doi: 10.7554/eLife.45545 (Jun 13, 2019)

Invited review: "NMDA receptor hypofunction for schizophrenia revisited: Perspectives from epigenetic mechanisms"
Melissa A. Snyder and Wen-Jun Gao
Schizophrenia Research. [Epub ahead of print] pii: S0920-9964(19)30104-5. doi: 10.1016/j.schres.2019.03.010 (Apr 9, 2019)

"Selective vulnerability of dorsal raphe-medial prefrontal cortex projection neurons to corticosterone-induced hypofunction"
Prouty EW, Chandler DJ, Gao WJ, Waterhouse BD
Eur J Neurosci. [Epub ahead of print] PubMed PMID: 30687960 (Jan 28, 2019)

"Neurons in rat orbitofrontal cortex and medial prefrontal cortex exhibit distinct responses in reward and strategy-update in a risk-based decision-making task"
Dan-Dan Hong, Wen-Qiang Huang, Ai-Ai Ji, Sha-Sha Yang, Hui Xu, Ke-Yi Sun, Aihua Cao, Wen-Jun Gao, Ning Zhou*, Ping Yu*
Metabolic Brain Disease, 34(2):417-429, Epub 2018 Dec 8, PubMed PMID: 30535618 (Apr 2019)

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"Absence of associative motor learning and impaired time perception in a rare case of complete cerebellar agenesis"
Bing Wu, Juan Yao, Guang-yan Wu, Xuang Li, Wen-Jun Gao*, Rong Wei*, Jian-Feng Sui*
(*corresponding authors)
Neuropsychologia, 117-551-557.  PMID: 30031016 (2018)

"The histone demethylase KDM6B in the medial prefrontal cortex epigenetically regulates cocaine reward memory"
Yu-Xiang Zhang, Rita C. Akumuo, Rodrigo A. España, Chun-Xia Yan*, Wen-Jun Gao*, and Yan-Chun Li*
(*corresponding authors)
Neuropharmacology, 141: 113-125.  PMID: 30165076 (2018)

"Juvenile treatment with mGluR2/3 agonist prevents schizophrenia-like phenotypes in adult by acting through GSK3b"
Xing B, Han G, Wang MJ, Snyder MA, Gao WJ
Neuropharmacology, 137:359-371 (2018)

Yang SS, Li YC, Coley AA, Chamberlin LA, Yu P*, Gao WJ*
Frontiers in Synaptic Neuroscience 10(7):1-12 (2018)

Ferguson BR and Gao WJ*
Frontiers in Neural Circuits. 12:37 (2018)

Monaco SA, Ferguson BR, and Gao WJ*
Front Cell Neurosci, 12:16 (2018)

"Thalamic control of cognition and social behavior via regulation of GABAergic signaling and E/I balance in the medial prefrontal cortex"
Ferguson BR and Gao WJ*
Biological Psychiatry 83:665-679 (2018)
Commentary: (Drexel ID required to access)
Fan Z and Hu H
Biological Psychiatry, Volume 83, Issue 8, Pages 630-631 (April 15, 2018)

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"PSD95: A synaptic protein implicated in schizophrenia or autism?"
Coley AA and Gao WJ*
Prog Neuropsychopharmacol Biol Psychiatry. 82:187-194. 2017, Nov 21. pii: S0278-5846(17)30658-9. doi: 10.1016/j.pnpbp.2017.11.016. [Epub ahead of print] Review. (2018)

"Psychostimulants As Cognitive Enhancers in Adolescents: More Risk than Reward?"
Urban KR and Gao WJ*
Front Public Health, 5:260. Sep 26;5:260. doi: 10.3389/fpubh.2017.00260. eCollection 2017. (2017)

Gulchina Y, Xu SJ, Snyder MA, Elefant F, Gao WJ*
J of Neurochemistry, 143(3):320-333. 2017 Jun 19. doi: 10.1111/jnc.14101 (2017)
: An Editorial Highlight for 'Epigenetic mechanisms underlying NMDA receptor hypofunction in the prefrontal cortex of juvenile animals in the MAM model for schizophrenia' on page 320. (Drexel ID required to access)
Zhu X, Gomes FV, Grace AA
J Neurochem. 2017 Nov;143(3):264-267. doi: 10.1111/jnc.14133. Epub 2017 Sep 5. PMID: 28872674

"A Clinically-Relevant Dose of Methylphenidate Enhances Synaptic Inhibition in the Juvenile Rat Prefrontal Cortex"
Urban K, Li YC, Xing B, Gao WJ
Journal of Reward Deficiency Syndrome & Addiction Science, in press (2017)

Li ML, Gulchina Y, Monaco SA, Xing B, Ferguson BR, Li YC, Li F, Hu XQ, Gao WJ
Neurobiology of Learning and Memory, 140:52-61 (2017)

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Xing B, Li YC and Gao WJ
Neuropsychopharmacology, 41(13) (2016)

"Disruption of Akt signaling decreases dopamine sensitivity in modulation of inhibitory synaptic transmission in rat prefrontal cortex"
Li YC, Yang SS and Gao WJ
Neuropharmacology, 108:403-414. http://ac.els-cdn.com/S0028390816302003/1-s2.0-S0028390816302003-main.pdf (2016)

"Norepinephrine versus Dopamine and their Interaction in Modulating Synaptic Function in the Prefrontal Cortex"
Xing B, Li YC and Gao WJ
Brain Research 1641 (Pt B):217-233. http://ac.els-cdn.com/S0006899316000172/1-s2.0-S0006899316000172-main.pdf (invited review, 2016)

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"LY395756, an mGluR2 agonist and mGluR3 antagonist, enhances NMDA receptor expression and function in the normal adult rat prefrontal cortex, but fails to improve working memory and reverse MK801-induced working memory impairment"
Meng-Lin (Merry) Li, Shasha Yang, Xing B, Brielle Ferguson, Gulchina Y, Li YC, Feng Li*, Xi-Quan Hu* and Gao WJ*
Experimental Neurology 273:190-201. http://ac.els-cdn.com/S0014488615300807/1-s2.0-S0014488615300807-main.pdf (2015)

"NR2B subunit in the prefrontal cortex: A double-edged sword for working memory function and psychiatric disorders"
Monaco SA#, Gulchina Y# and Gao WJ (# These authors contribute equally)
Neuroscience and Biobehavioral Reviews 56:127-138. http://ac.els-cdn.com/S0149763415001761/1-s2.0-S0149763415001761-main.pdf (2015)

Meng-Lin (Merry) Li, Xi-Quan Hu, Feng Li and Gao WJ
Progress in Neuropsychopharmacology & Biological Psychiatry 60:66-76 (review, 2015)

Ferguson BR and Gao WJ
Frontiers in Human Neuroscience, 8(1027):1-10 (invited review, 2015)

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Daniel J. Chandler, Gao WJ and Barry D. Waterhouse
PNAS, 111(18):6816-6821 (2014)

Daniel J. Chandler, Barry D. Waterhouse and Gao WJ
Frontiers in Neural Circuits, 8:53 (invited review, May 23, 2014)

Urban KR and Gao WJ
Frontiers in Systems Neuroscience, 8:38 (invited review, May 13, 2014)
Related Media:

Jonathan Pitcher^1,2*, Anna Abt¹*, Jaclyn Myers¹**, Rachel Han¹, Melissa Snyder³, Alessandro Graziano¹, Michele Kutzler^4,2, Fernando Garcia⁵, Gao WJ³, Tracy Fisher-Smith⁶, Jay Rappaport⁶ and Olimpia Meucci^1,2***
Journal of Clinical Investigation, 124(2)656-668 (2014)

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Urban KR and Gao WJ
Medical Hypotheses, 81:988-994 (2013)

"Selective suppression of excitatory synapses on GABAergic interneurons by norepinephrine in prefrontal cortical microcircuitry"
Huai-Xing Wang, Barry Waterhouse and Gao WJ
Neuroscience, 246:312-328. http://ac.els-cdn.com/S030645221300420X/1-s2.0-S030645221300420X-main.pdf (2013)

"Group II metabotropic glutamate receptor agonist LY379268 regulates AMPA receptor trafficking in prefrontal cortical neurons" [PDF]
Wang MJ, Li YC, Melissa A. Snyder, Huai-Xing Wang, Feng Li* and Gao WJ*
PLOS ONE 8(4):e61787 (2013)

Melissa A. Snyder and Gao WJ
Frontiers in Cellular Neuroscience, 7:31 (invited review, 2013)

Urban KR, Li YC and Gao WJ
Neurobiology of Learning and Memory, 101:65-74 (2013)

Melissa A. Snyder, Alicia E. Adelman and Gao WJ
Neuropsychopharmacology, 38:328-340 (2013)

Urban KR and Gao WJ
Journal of Attention Disorders, 101:65-74 [Epub ahead of print] (Aug. 24, 2013)

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Li YC, Wang MJ and Gao WJ
Joural of Neurochemistry, 122:308-320 (2012)

Kimberly Urban, Barry Waterhouse and Gao WJ
Biological Psychiatry, 72(10):880-888 (2012)

Huai-Xing Wang and Gao WJ
Neuropharmacology, 62:1808-1822 (2012)

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Li YC, Christoph Kellendonk , Eleanor H. Simpson, Eric R. Kandel and Gao WJ
PNAS, 108(29):12107-112 (2011) - Commentary in Schizophrenia Research Forum []

Agster K, Clark B, Gao WJ, Shumsky J, Wang HX, Berridge C and Waterhouse B
Anatomical Record, 294:1698-1712 (invited review, 2011)

Dong Xi*, Li YC*, Melissa A. Snyder*, Ruby Y. Gao, Alicia E. Adelman, Wentong Zhang, Jed S. Shumsky and Gao WJ (* these authors contribute equally)
Neuropsychopharmacology, 36:1260-1274 (2011)

Li YC and Gao WJ
Neuroscience & Biobehavioral Reviews, 35:645-654 (2011)

Huai-Xing Wang and Gao WJ
The Journal of Physiology, 588(15):2823-2838 (2010) [selected for Faculty of 1000 Medicine and evaluated by Dr. Antonio Pisani]

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Jian-Li Hu *, Gang Liu *, Li YC *, Gao WJ and Yue-Qiao Huang (* these authors contribute equally)
Molecular Brain, 3:20 (2010)

Li YC ¹, Gang Liu ¹, Jian-Li Hu ¹, Gao WJ* and Yue-Qiao Huang* (¹ these authors contribute equally)
The Journal of Neurochemistry, 114:62-73 (2010)

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Li YC, Dong Xi, Joy Roman, Yue-Qiao Huang and Gao WJ
Journal of Neuroscience, 29(49):15551-15563 (2009)

Ji Y, Yang F, Papaleo F, Wang HX, Gao WJ, Weinberger DR and Lu B
PNAS, 106:19593-19598 (2009)

Xi D, Zhang W, Wang HX, Stradtman GG III and Gao WJ
Int J Neuropsychopharmacol, 12:1395-1408 (2009)

Wang HX and Gao WJ
Neuropsychopharmacology, 34(8):2028-2040 (2009)

Xi D, Keeler B, Zhang W, Houle JD and Gao WJ
Journal of Neuroscience Method, 176:172-181 (2009)

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Wang HX, Stradtman GG III, Wang X-J and Gao WJ
PNAS, 105(43):16791-16796 (2008)

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"Acute clozapine suppresses synchronized pyramidal synaptic network activity by increasing inhibition in the prefrontal cortex"
Gao WJ
The Journal of Neurophysiology, 97:1196-1208. https://jn.physiology.org/content/97/2/1196.long (2007)

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"NMDA receptor-mediated epileptiform persistent activity requires calcium release from internal stores"
Gao WJ and Goldman-Rakic PS
Experimental Neurology, 197:495-504. http://ac.els-cdn.com/S0014488605003742/1-s2.0-S0014488605003742-main.pdf (2006)

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Gao WJ and Zheng ZH
The Journal of Comparative Neurology, 476:174-185 (2004)

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Gao WJ and Goldman-Rakic PS
PNAS, 100(5):2836-41 (2003)

Gao WJ, Wang Y and Goldman-Rakic PS
The Journal of Neuroscience, 23:1622-30 (2003)

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"Presynaptic regulation of recurrent excitation by D1 receptor in prefrontal circuits" [PDF]
Gao WJ, Krimer LS and Goldman-Rakic PS
PNAS, 98:295-300 (2001)

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"Development of inhibitory circuitry in visual and auditory cortex of postnatal ferrets: immunocytochemical localization of parvalbumin and calbindin-containing neurons"
Gao WJ, Wormington AB, Newman DE and Pallas SL
The Journal of Comparative Neurology, 422:140-157 (2000)

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"Cross-modal reorganization of horizontal connectivity in auditory cortex without altering thalamocortical input"
Gao WJ and Pallas SL
The Journal of Neuroscience, 19(18):7940-7950 (1999)

"Development of inhibitory circuitry in visual and auditory cortex of postnatal ferrets: immunocytochemical localization of GABAergic neurons"
Gao WJ, Newman DE, Wormington AB and Pallas SL
The Journal of Comparative Neurology, 409(2):261-273 (1999)

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“Postsynaptic integration and plasticity in the prefrontal cortex”
Paul G. Anastasiades, Guillermo Gonzalez-Burgos, and Wen-Jun Gao
In: The Handbook of Dopamine, Edited by Mark Walton and Stephen Cragg, Oxford University Press (2025)

"NR2B subunit in the prefrontal cortex: A double-edged sword for working memory function and psychiatric disorders"
Monaco SA#, Gulchina Y# and Gao WJ (# these authors contributed equally)
Neuroscience and Biobehavioral Reviews, 56:127-138 (accepted, 2015)

"Perspectives on the mGluR2/3 agonists as a therapeutic target for schizophrenia: Still promising or a dead end?"
Li ML, Xi-Quan Hu, Feng Li, Gao WJ
Progress in Neuropsychopharmacology & Biological Psychiatry, 60:66-76 (review, 2015)

"Development of thalamocortical connections between the mediodorsal nucleus of the thalamus and the prefrontal cortex and its implication in executive and cognitive function"
Ferguson BR and Gao WJ
Frontiers in Human Neuroscience, 8(1027):1-10 (invited review, 2015)

"New Perspectives on Catecholaminergic Regulation of Executive Circuits: Evidence for Independent Modulation of Prefrontal Functions by Midbrain Dopaminergic and Noradrenergic Neurons"
Daniel J. Chandler, Barry D. Waterhouse and Gao WJ
Frontiers in Neural Circuits, May 23, 8:53 (invited review, 2014)

"Performance enhancement at the cost of potential brain plasticity: neural ramifications of nootropic drugs in the healthy developing brain"
Urban KR and Gao WJ
Frontiers in Systems Neuroscience, May 13, featured article (invited review, 2014)

"NMDA hypofunction as a convergence point for progression and symptoms of schizophrenia" Melissa A. Snyder and Gao WJ
Frontiers in Cellular Neuroscience, 7:31 (invited review, 2013)

"Evolution of the Study of Methylphenidate and its Actions on the Adult versus Juvenile Brain"
Urban KR and Gao WJ
Journal of Attention Disorders (in press, 2012)

"GSK-3 and hyperdopaminergic behaviors"
Li YC and Gao WJ
Neuroscience & Biobehavioral Reviews, 35:645-654 (2011)

"Experimental strategies for investigating drug actions in ADHD and related attention disorders"
Agster K, Clark B, Gao WJ, Shumsky J, Wang HX, Berridge C and Waterhouse B
Anatomical Record, 294:1698-1712 (invited review, 2011)

"Dopaminergic and Glutamatergic Dysfunctions in the Neuropathophysiology of Schizophrenia"
Gao WJ
In: Dopamine: Functions, Regulation and Health Effects, edited by Endo Kudo and Yuriko Fujii. Nova Publishers (2011)

"The unique properties of the prefrontal cortex and mental illness"
Gao WJ, Huai-Xing Wang, Melissa A. Snyder and Li YC
In: When Things Go Wrong – Diseases and Disorders of the Human Brain, edited by Theo Mantamadiotis, Intech Publisher (2012)