91ÖÆƬ³§

Education:

• Postdoctoral fellow, National Institutes of Health, 2022
• PhD, Physical Chemistry, Massachusetts Institute of Technology, 2018
• BS, Physics, University of Seoul, 2006

Curriculum Vitae:

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Research Interests:

• Neurodegenerative protein aggregation
• Membrane associated amyloid fibrils
• Molecular structures, dynamics, and intermolecular interactions of biological macro molecules
• Solid-state NMR and Cryo-electron microscopy (Cryo-EM)

Bio:

Myungwoon Lee received her BS in Physics at University of Seoul (Korea). After working at Samsung Electronics (Korea) as a senior research engineer, she started her graduate research and received her PhD in Physical Chemistry at MIT. After her postdoctoral research at NIH, she joined the faculty at 91ÖÆƬ³§ as an assistant professor in January 2023.

Selected Publications:

Amyloid fibrils

• M. Lee, U. Ghosh, K.R. Thurber, M. Kato, R. Tycko, “Molecular Structure and Interactions within Amyloid-Like Fibrils Formed by a Low Complexity Protein Sequence from FUS”, Nat. Commun. 11, 5735 (2020).   
• M. Lee, T. Wang, O.V. Makhlynets, Y. Wu, N.P. Polizzi, H. Wu, P.M. Gosavi, J. Stöhr, I.V. Korendovych, W.F. DeGrado, M. Hong, “Zinc-Binding Structure of a Catalytic Amyolid from Solid-State NMR”, Proc. Natl. Acad. Sci. USA 114 (24), 6191-6196 (2017).  

Viral fusion proteins 

• M. Lee, C.M. Morgan, M. Hong, “Fully Hydrophobic HIV gp41 Adopts a Hemifusion-like Conformation in Phospholipid Bilayers”, J. Biol. .Chem. 294, 14732-14744 (2019).
 
• M. Lee, B. Kwon, A. Waring, M. Hong, “Oligomeric Structure and Three-dimensional Fold of the HIV gp41 MPER and Transmembrane Domain in Phospholipid Bilayers”, J. Am. Chem. Soc. 140 (26), 8246-8259 (2018).