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Aleister Saunders, PhD

Aleister Saunders, PhD

Executive Vice Provost for Research & Innovation
Professor
Department of Biology
Office: 104 Left Bank
Aleister.Saunders@drexel.edu
Phone: 215.895.6091
Lab Location: PISB 401 C2
Lab Phone: 215.895.6884
Additional Sites:

Provost’s Office Leadership


Education:

  • Post-doctoral Training, Harvard Medical School
  • PhD, University of North Carolina, Chapel Hill
  • BS, Pennsylvania State University

Bio:

Aleister Saunders’ research focuses on identifying and characterizing genes and pathways involved in Alzheimer’s disease pathogenesis. Utilizing a variety of AD models, his work has been funded by NIH, NSF, and foundations. As Drexel’s Executive Vice Provost for Research & Innovation, Dr. Saunders has provided University-level research and innovation leadership since 2014. He is principally responsible for helping 91制片厂 achieve Carnegie Classification as a “Very High Research Activity” (R1) institution, first attained in 2018 and reaffirmed in 2022. In 2020, Drexel also achieved recognition as the top-ranked mid-sized University for Innovation impact. Aleister oversees Drexel's successful collaboration with MIT to win and manage the Manufacturing USA institute Advanced Functional Fabrics of America. Regionally, Aleister has facilitated Drexel’s academic/industrial partnership with Spark Therapeutics to create a state-of-the-art gene therapy facility on Drexel’s campus. He also manages Drexel’s response to federal regulations related to undue foreign influence while maintaining academic freedom.

Research Interests

My laboratory focuses its research efforts on identifying and characterizing genes and pathways that are involved in pathogenesis of Alzheimer鈥檚 disease (AD). We believe our efforts will lead to the identification of novel therapeutic strategies to delay or prevent onset of AD. To this end we have worked collaboratively to develop novel animal models of AD that we utilize to confirm and extend our observations from cellular models. The research in the lab is carried out by post-doctoral fellows, graduate and undergraduate students that work on individual and group projects and always in constant interaction with me. I am committed to creating an interactive, nurturing and exciting research experience for all of the members of my laboratory. Please feel free to contact myself or the members of my lab if you have any questions.

Selected Publications:

  • Vorobyeva AG, Saunders AJ. . Cilia. 2018;7:5. doi: 10.1186/s13630-018-0059-y. eCollection 2018. PubMed PMID: 30140428; PubMed Central PMCID: PMC6098584.
  • Ward J, Wang H, Saunders AJ, Tanzi RE, Zhang C. Discov Med. 2017 Feb;23(125):121-128. PubMed PMID: 28371615; PubMed Central PMCID: PMC5524192.
  • Crenshaw E, Leung BP, Kwok CK, Sharoni M, Olson K, Sebastian NP, Ansaloni S, Schweitzer-Stenner R, Akins MR, Bevilacqua PC, Saunders AJ. PLoS One. 2015;10(11):e0143160. doi: 10.1371/journal.pone.0143160. eCollection 2015. PubMed PMID: 26618502; PubMed Central PMCID: PMC4664259.
  • Wang H, Sang N, Zhang C, Raghupathi R, Tanzi RE, Saunders A. Biochemistry. 2015 May 12;54(18):2806-16. doi: 10.1021/acs.biochem.5b00329. Epub 2015 Apr 28. PubMed PMID: 25910068; PubMed Central PMCID: PMC4521409.
  • Vorobyeva AG, Lee R, Miller S, Longen C, Sharoni M, Kandelwal PJ, Kim FJ, Marenda DR, Saunders AJ. J Biol Chem. 2014 Nov 28;289(48):33258-74. doi: 10.1074/jbc.M114.591792. Epub 2014 Oct 3. PubMed PMID: 25281744; PubMed Central PMCID: PMC4246084.
  • Mhatre SD, Michelson SJ, Gomes J, Tabb LP, Saunders AJ, Marenda DR. Exp Neurol. 2014 Nov;261:772-81. doi: 10.1016/j.expneurol.2014.08.021. Epub 2014 Aug 27. PubMed PMID: 25173219.
  • Wang H, Saunders AJ. Discov Med. 2014 Jul-Aug;18(97):41-50. Review. PubMed PMID: 25091487.
  • Mhatre SD, Satyasi V, Killen M, Paddock BE, Moir RD, Saunders AJ, Marenda DR. Dis Model Mech. 2014 Mar;7(3):373-85. doi: 10.1242/dmm.012104. Epub 2014 Jan 30. PubMed PMID: 24487408; PubMed Central PMCID: PMC3944497.
  • Reza MA, Mhatre SD, Morrison JC, Utreja S, Saunders AJ, Breen DE, Marenda DR. Fly (Austin). 2013 Apr-Jun;7(2):105-11. doi: 10.4161/fly.24110. Epub 2013 Apr 1. PubMed PMID: 23644900; PubMed Central PMCID: PMC3732329.
  • Mhatre SD, Paddock BE, Saunders AJ, Marenda DR. J Alzheimers Dis. 2013;33(1):3-16. doi: 10.3233/JAD-2012-121204. Review. PubMed PMID: 22886023.
  • Hooli BV, Mohapatra G, Mattheisen M, Parrado AR, Roehr JT, Shen Y, Gusella JF, Moir R, Saunders AJ, Lange C, Tanzi RE, Bertram L. Neurology. 2012 Apr 17;78(16):1250-7. doi: 10.1212/WNL.0b013e3182515972. Epub 2012 Apr 4. PubMed PMID: 22491860; PubMed Central PMCID: PMC3324321.